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Lower urinary tract symptoms

MedGen UID:
452620
•Concept ID:
C0574785
•
Sign or Symptom
Synonyms: Lower Urinary Tract Symptom; Lower Urinary Tract Symptoms
SNOMED CT: Lower urinary tract symptoms (307541003); LUTS - lower urinary tract symptoms (307541003)

Definition

Symptoms that result from pathologic processes affecting the urinary bladder and/or urethra. They include urinary frequency and urgency, dysuria, nocturia, incomplete voiding, and poor stream during urination. [from NCI]

Professional guidelines

PubMed

Pelvic-floor function, dysfunction, and treatment.
Quaghebeur J, Petros P, Wyndaele JJ, De Wachter S
Eur J Obstet Gynecol Reprod Biol 2021 Oct;265:143-149. Epub 2021 Aug 28 doi: 10.1016/j.ejogrb.2021.08.026. PMID: 34492609
Testosterone Therapy in Men With Hypogonadism: An Endocrine Society Clinical Practice Guideline.
Bhasin S, Brito JP, Cunningham GR, Hayes FJ, Hodis HN, Matsumoto AM, Snyder PJ, Swerdloff RS, Wu FC, Yialamas MA
J Clin Endocrinol Metab 2018 May 1;103(5):1715-1744. doi: 10.1210/jc.2018-00229. PMID: 29562364
Diagnosis and treatment of urinary tract infections across age groups.
Chu CM, Lowder JL
Am J Obstet Gynecol 2018 Jul;219(1):40-51. Epub 2018 Jan 2 doi: 10.1016/j.ajog.2017.12.231. PMID: 29305250

Recent clinical studies

Etiology

The Role of Aquablation for the Surgical Treatment of LUTS/BPH.
Saadat H, Elterman DS
Curr Urol Rep 2019 Jun 21;20(8):46. doi: 10.1007/s11934-019-0905-5. PMID: 31227924
Inflammation, Voiding and Benign Prostatic Hyperplasia Progression.
Lloyd GL, Ricke WA, McVary KT
J Urol 2019 May;201(5):868-870. doi: 10.1097/JU.0000000000000049. PMID: 30694937Free PMC Article
What's New in Epidemiology?
Malde S, Cartwright R, Tikkinen KAO
Eur Urol Focus 2018 Jan;4(1):11-13. Epub 2018 Feb 12 doi: 10.1016/j.euf.2018.02.003. PMID: 29449167
The neurogenic bladder and the physiatrist.
DI Benedetto P
Eur J Phys Rehabil Med 2017 Dec;53(6):972-974. Epub 2017 Nov 3 doi: 10.23736/S1973-9087.17.05063-8. PMID: 29099163
Testosterone and the Prostate: Artifacts and Truths.
DeLay KJ, Kohler TS
Urol Clin North Am 2016 Aug;43(3):405-12. doi: 10.1016/j.ucl.2016.04.011. PMID: 27476133

Diagnosis

Introduction.
Bhatia S
Tech Vasc Interv Radiol 2020 Sep;23(3):100686. Epub 2020 Oct 5 doi: 10.1016/j.tvir.2020.100686. PMID: 33308531
Benign Prostatic Hyperplasia.
Langan RC
Prim Care 2019 Jun;46(2):223-232. Epub 2019 Apr 1 doi: 10.1016/j.pop.2019.02.003. PMID: 31030823
Bladder Bowel Dysfunction.
Aguiar LM, Franco I
Urol Clin North Am 2018 Nov;45(4):633-640. Epub 2018 Sep 7 doi: 10.1016/j.ucl.2018.06.010. PMID: 30316317
Clinical implications of underactive bladder.
Ko KJ, Lee CU, Lee KS
Investig Clin Urol 2017 Dec;58(Suppl 2):S75-S81. Epub 2017 Nov 22 doi: 10.4111/icu.2017.58.S2.S75. PMID: 29279879Free PMC Article
Practical uroflowmetry.
Jarvis TR, Chan L, Tse V
BJU Int 2012 Dec;110 Suppl 4:28-9. doi: 10.1111/bju.11617. PMID: 23194121

Therapy

Con: Preoperative urodynamics still has a role for BPH patients after the UPSTREAM trial.
Baboudjian M, Uleri A, Pradere B
Fr J Urol 2024 Jun;34(6):102637. Epub 2024 Apr 8 doi: 10.1016/j.fjurol.2024.102637. PMID: 38599323
Recent advances in managing benign prostatic hyperplasia: The Rezūm System.
Guelce D, Thomas D, Elterman D, Chughtai B
F1000Res 2018;7 Epub 2018 Dec 10 doi: 10.12688/f1000research.15851.1. PMID: 30631433Free PMC Article
Prostatic artery embolization for benign prostatic hyperplasia: a review.
Young S, Golzarian J
Curr Opin Urol 2018 May;28(3):284-287. doi: 10.1097/MOU.0000000000000495. PMID: 29538167
Bipolar or monopolar transurethral resection for benign prostatic hyperplasia?
Inzunza G, Rada G, Majerson A
Medwave 2018 Jan 17;18(1):e7134. doi: 10.5867/medwave.2018.01.7134. PMID: 29351269
Electroneurostimulation for the management of bladder bowel dysfunction in childhood.
Wright AJ, Haddad M
Eur J Paediatr Neurol 2017 Jan;21(1):67-74. Epub 2016 May 27 doi: 10.1016/j.ejpn.2016.05.012. PMID: 27328864

Prognosis

Inflammation, Voiding and Benign Prostatic Hyperplasia Progression.
Lloyd GL, Ricke WA, McVary KT
J Urol 2019 May;201(5):868-870. doi: 10.1097/JU.0000000000000049. PMID: 30694937Free PMC Article
Bladder Bowel Dysfunction.
Aguiar LM, Franco I
Urol Clin North Am 2018 Nov;45(4):633-640. Epub 2018 Sep 7 doi: 10.1016/j.ucl.2018.06.010. PMID: 30316317
Prostate Cancer in Primary Care.
Merriel SWD, Funston G, Hamilton W
Adv Ther 2018 Sep;35(9):1285-1294. Epub 2018 Aug 10 doi: 10.1007/s12325-018-0766-1. PMID: 30097885Free PMC Article
The Epidemiology of Benign Prostatic Hyperplasia Associated with Lower Urinary Tract Symptoms: Prevalence and Incident Rates.
Egan KB
Urol Clin North Am 2016 Aug;43(3):289-97. doi: 10.1016/j.ucl.2016.04.001. PMID: 27476122
Medium-term Outcomes of Urolift (Minimum 12 Months Follow-up): Evidence From a Systematic Review.
Jones P, Rajkumar GN, Rai BP, Aboumarzouk OM, Cleaveland P, Srirangam SJ, Somani BK
Urology 2016 Nov;97:20-24. Epub 2016 May 18 doi: 10.1016/j.urology.2016.05.003. PMID: 27208817

Clinical prediction guides

Age-related changes for the predictors of benign prostatic hyperplasia in Chinese men aged 40 years or older.
Shao WH, Zheng CF, Ge YC, Chen XR, Zhang BW, Wang GL, Zhang WD
Asian J Androl 2023 Jan-Feb;25(1):132-136. doi: 10.4103/aja202223. PMID: 35532557Free PMC Article
Role of Urodynamic Studies in Management of Benign Prostatic Obstruction: A Guide for Interventional Radiologists.
Gomez C, Bhatia S, Carnevale FC, Narayanan G
J Vasc Interv Radiol 2017 Jan;28(1):126-133. Epub 2016 Nov 10 doi: 10.1016/j.jvir.2016.09.003. PMID: 27840041
Contemporary surgical management of female urethral stricture disease.
Osman NI, Chapple CR
Curr Opin Urol 2015 Jul;25(4):341-5. doi: 10.1097/MOU.0000000000000186. PMID: 26049879
Pelvic ultrasound evaluation for benign prostatic hyperplasia: prediction of obstruction.
Rukstalis DB
Curr Urol Rep 2014 May;15(5):403. doi: 10.1007/s11934-014-0403-8. PMID: 24658830
Uroflowmetry and evaluation of voiding disorders.
Ather MH, Memon A
Tech Urol 1998 Sep;4(3):111-7. PMID: 9800886

Recent systematic reviews

"Nocturia and obstructive sleep apnea syndrome: A systematic review".
Di Bello F, Napolitano L, Abate M, Collà Ruvolo C, Morra S, Califano G, Capece M, Creta M, Scandurra C, Muzii B, Di Nola C, Bochicchio V, Nocini R, Abbate V, Maldonato NM, Dell'Aversana Orabona G, Longo N, Cantone E
Sleep Med Rev 2023 Jun;69:101787. Epub 2023 Apr 29 doi: 10.1016/j.smrv.2023.101787. PMID: 37167825
European Association of Urology Guidelines on the Diagnosis and Management of Female Non-neurogenic Lower Urinary Tract Symptoms. Part 1: Diagnostics, Overactive Bladder, Stress Urinary Incontinence, and Mixed Urinary Incontinence.
Nambiar AK, Arlandis S, Bø K, Cobussen-Boekhorst H, Costantini E, de Heide M, Farag F, Groen J, Karavitakis M, Lapitan MC, Manso M, Arteaga SM, Riogh ANA, O'Connor E, Omar MI, Peyronnet B, Phé V, Sakalis VI, Sihra N, Tzelves L, van Poelgeest-Pomfret ML, van den Bos TWL, van der Vaart H, Harding CK
Eur Urol 2022 Jul;82(1):49-59. Epub 2022 Feb 23 doi: 10.1016/j.eururo.2022.01.045. PMID: 35216856
Minimally invasive treatments for lower urinary tract symptoms in men with benign prostatic hyperplasia: a network meta-analysis.
Franco JV, Jung JH, Imamura M, Borofsky M, Omar MI, Escobar Liquitay CM, Young S, Golzarian J, Veroniki AA, Garegnani L, Dahm P
Cochrane Database Syst Rev 2021 Jul 15;7(7):CD013656. doi: 10.1002/14651858.CD013656.pub2. PMID: 34693990Free PMC Article
Benign prostate hyperplasia and nutrition.
Das K, Buchholz N
Clin Nutr ESPEN 2019 Oct;33:5-11. Epub 2019 Aug 12 doi: 10.1016/j.clnesp.2019.07.015. PMID: 31451276
Medium-term Outcomes of Urolift (Minimum 12 Months Follow-up): Evidence From a Systematic Review.
Jones P, Rajkumar GN, Rai BP, Aboumarzouk OM, Cleaveland P, Srirangam SJ, Somani BK
Urology 2016 Nov;97:20-24. Epub 2016 May 18 doi: 10.1016/j.urology.2016.05.003. PMID: 27208817

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